Vacuum And Hydraulic System of Lyophilization Equipment

The moisture in the product can be sublimated quickly only under vacuum to achieve the purpose of drying. The vacuum system of Lyophilization Equipment consists of a freeze-drying box, a condenser, a vacuum valve, a vacuum pump, a vacuum line, and a vacuum measuring component.

The system of Lyophilization Equipment uses a vacuum pump set to form a powerful suction capacity, forming a vacuum in the drying chamber and the condenser, on the one hand, causing the water in the drying chamber to evaporate under vacuum. The vacuum degree of the vacuum system should match the sublimation temperature of the product and the temperature of the condenser. If the degree of vacuum is too high or too low, it is not conducive to sublimation. The vacuum degree of the drying box should be controlled within the set range. Shortening the sublimation cycle of the product, the premise of vacuum control is that the vacuum system itself must have a small leakage rate. The vacuum pump has a large enough power reserve to ensure that the ultimate vacuum is reached.

The hydraulic system of Lyophilization Equipment is a special device that presses the stopper into the bottle mouth at the end of freeze drying. The hydraulic system is located at the top of the drying box and is mainly composed of an electric motor, an oil pump, a check valve, a relief valve, a solenoid valve, a fuel tank, a cylinder and a pipe.

At the end of Lyophilization, the hydraulic plugging system starts to work, and under vacuum conditions, the upper shelf is slowly moved downward to complete the product bottle stoppering task. The hydraulic oil pump station, oil cylinder, etc. are installed in the top of the freeze-drying tank. Under the drive of the hydraulic pump station, the plate layer is lifted up and down in the tank to facilitate the entry and exit of the tank and the cleaning work.

The seal of the lower part of the piston rod of the cylinder uses O-type silicon. The rubber seal ensures that oil will not be contaminated and the drug will be contaminated. The piston uses a YX polyurethane seal. The electromagnetic reversing valve and the hydraulic balancing valve are accurate in signal transmission, and do not slip without vibration.